Recent studies on the biology of adipose tissue have identified it as an active endocrine organ other than the storage site for energy. Significant advances in the study of white, brown, and beige adipose tissues, functions of adipocyte differentiation, and their roles in metabolic homeostasis are presented. Several studies also highlight the role of inflammation and fibrosis of adipose tissues and their crosstalk with other organs in obesity and metabolic disorders. The IOMC has been a venue for discussing state-of-the-art discoveries in adipose tissue biology, facilitating collaboration, and enhancing global efforts in combating obesity and metabolic diseases through translational research. Targeting the plasticity and browning of adipose tissue holds great promise for innovative therapeutic strategies.