Although the development of obesity undoubtedly involves changes in gene expression, it is epigenetic since it requires no variation within the underlying DNA sequence. Epigenetic marks due to altered environmental conditions like diet, stress, and toxicants thus affect metabolic pathways that result in obesity. The conference would thus be a better platform to present cutting-edge epigenetics and metabolism-based research and create a think-tank for further collaboration that uncovers newer interventions and strategies to manage obesity and its metabolic sequelae. These may then be passed on from one generation to the next, contributing to the intergenerational transmission of obesity. Understanding the underlying epigenetic mechanisms opens new avenues for early interventions and personalized treatments.